a tool for identifying drug-targetable redox-active disulphides

Major allergen Can f 1

Intramolecular

Cysteine 78 and cysteine 169

A redox-regulated disulphide may form within Major allergen Can f 1 between cysteines 78 and 169.

Details

Redox score ?

87

PDB code

Structure name

crystal structure of the dog lipocalin allergen can f 1

Structure deposition date

2020-12-29

Thiol separation (Å)

2

Half-sphere exposure sum ?

48

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

78

Residue number B

169

Peptide name

Major allergen Can f 1

Ligandability

Cysteine 78 of Major allergen Can f 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 169 of Major allergen Can f 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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